Cluster 3: Translational Pathways
Work Package 2 | Patient Involvement
Dr. Eric Gifford is currently leading the MSD Research & Development IT organization in Singapore. Previous to this assignment he worked at Merck Research Labs in Boston, MA and West Point, PA applying machine learning and data analytics to translational medicine problems including drug safety. He joins with a strong commitment to advancing the science and relevance of remote patient monitoring to gain new scientific insights. He is also a strong advocate for patient involvement and citizen science based approaches to discover improved treatments and cures for unmet medical needs. Eric joined MSD in 2013 from Pfizer where he led a number of initiatives in computational ADME/Tox searching for relationships between pharmaceutical agents, biological targets and physiological responses. Today his primary focus is on the digital transformation of drug discovery and development.
Til Wykes is Professor of Clinical Psychology and Rehabilitation and Vice Dean Psychology and Systems Sciences at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. She has been involved in research on rehabilitation for many years both in the development of services and the evaluation of innovative psychological treatments for psychosis. She founded and is now Co-Director of the Service User Research Enterprise (SURE), which employs expert researchers with experience of using mental health services.
She edits the Journal of Mental Health and is NIHR Senior Spokesperson on Mental Health Research. She was awarded a Damehood recently for her work in mental health.
Sara is a post-doctoral research associate in the psychology department at King’s College London. She facilitates patient involvement in the RADAR-CNS project. This includes the co-ordination of our patient advisory board. Her role also involves developing a better understanding of processes that improve engagement with mobile technologies in healthcare, using a combination of qualitative and quantitative methods.
Sara is a qualified clinical psychologist and has a PhD in neuropsychology. In her previous work she has researched the feasibility, acceptability and effectiveness of e-health interventions for treatment of mental health problems, including symptoms experienced by people with chronic physical health problems (such as acquired brain injury/stroke). She also has experience of evaluating the psychometric properties of measurement tools in psychology.
Sara has an interest in bringing her knowledge of clinical psychology and behavioural science to the field of e-health with the aim of better understanding the implementation of novel interventions and assessment resources, including remote measurement technology. An important part of this is applying a person-centred approach that focuses on the elements of care, support and treatment that matter most to the patient, their family and carers.
Work Package 9 | Clinical Pathways
Chris Hollis is Professor of Child & Adolescent Psychiatry at the University of Nottingham and Director of the NIHR MindTech Healthcare Technology Co-operative. He trained in psychiatry at the Maudsley Hospital and Institute of Psychiatry, where he was awarded an MRC Training Fellowship and completed his PhD on the long-term adult outcome adolescent-onset psychosis. As Director of MindTech, Chris is passionate about harnessing digital technology and building its evidence-base in mental healthcare by bringing together patients, clinicians, academics and technology developers. He was lead author of ‘Technological Innovations in Mental Healthcare’ in the 2013 Annual Report of England’s Chief medical Officer. Chris chaired the NICE Guideline for schizophrenia and psychosis in children and young people (2011-13) and is currently a member of the NICE ADHD (Update) Guideline Committee. He is a member of Innovate UK’s Digital Health Strategy Group.
Lies graduated as a clinical psychologist at the university of Leuven in Belgium. After her studies she went to Maastricht University where she finished her PhD at the faculty of Mental Health and NeuroScience (around imaging markers of Alzheimers disease). After a short period of being a post doc she decided to continue her career outside the academic setting and joined Janssen in 2014, started as an MSL, and promoted to Medical advisor in 2017. Lies is now working for 5 years in medical affairs at Janssen.
Jenny Jamnadas-Khoda is a Research Fellow in the NIHR MindTech MedTech Co-operative, based in the Institute of Mental Health at the University of Nottingham, UK. She trained in health services research at ScHARR, University of Sheffield before embarking on clinical neuroscience training at UCL Queen Square Institute of Neurology, where she worked for four years in the field of epilepsy research. More recently, Jenny has worked at the Institute of Mental Health, University of Nottingham, on a wide range of applied health research projects. This included a fellowship at Karolinska Institutet, Sweden exploring cognitive accessibility and technological use when ageing.
Jenny has extensive experience working with patients, public, healthcare professionals and service providers, and was elected a trustee of the charity Epilepsy Action from 2012-2016. Within the RADAR-CNS project, Jenny will be involved in Work Package 9 Clinical Pathways, looking at healthcare professionals’ experience and perception of remote measuring technology in clinical practice.
Michael is Senior Research Fellow in the NIHR MindTech MedTech Co-operative, based in the Institute of Mental Health at the University of Nottingham, UK.
He has spent 30 years in research and teaching in the areas of healthcare technology assessment, electronic engineering and computer science.
Additionally he is a member of Faculty of Engineering Bioengineering research group, holds an honorary contract with Nottingham Healthcare NHS Foundation Trust and is Health Economist in the Centre for Healthcare Equipment and Technology Adoption (CHEATA) based in the Nottingham University Hospitals NHS Trust.
In MindTech Mike contributes expertise in design and evaluation of digital health interventions and assistive technologies in mental health and dementia care. He has previously conducted health technology assessments and reviews for National Health Service organisation and industry and recently contributed to a British Standards Institute specification for quality in the development of mobile health apps (PAS 277). Details of publications and other grants are available via ORCID: https://orcid.org/0000-0001-5682-6360
Work Package 10 | Regulation
André W. Broekmans MD PhD is currently Director Regulatory Science at Lygature, The Netherlands.
He has more than twenty-five years regulatory experience, both with the Dutch regulatory agency (as Head of Clinical Assessment and as Chief Executive Officer resp., Dutch Medicines Evaluation Board) and with major pharmaceutical companies (senior management positions with MSD, Schering Plough, Organon). He was successful in gaining regulatory approval for a great number of medicines (small molecules, vaccines, biotech products). In all companies he was involved medical technology initiatives.
He built up his regulatory policy expertise by participating in EMA activities (as chair of the Management Board), ICH Steering Committee (as EFPIA representative) and international trade associations.
André has practiced as a general internist at the Leiden University Hospital where he also did his PhD in thrombosis research.
Steve is a regulatory professional with more than 25 years of applied strategic and tactical delivery of knowledge and experience in International Medical Technology Regulatory Affairs, Quality Assurance and Project Management working in various medical technologies including drug/device combination delivery systems, borderline drug/devices, software medical devices, digital health including ‘Apps’, In-Vitro Diagnostics/companion diagnostics, medical electrical equipment, cosmetics, consumer health products and food supplements.
