Cluster 3: Translational Pathways
Work Package 2 | Patient Involvement
Dr. Eric Gifford is currently leading the MSD Research & Development IT organization in Singapore. Previous to this assignment he worked at Merck Research Labs in Boston, MA and West Point, PA applying machine learning and data analytics to translational medicine problems including drug safety. He joins with a strong commitment to advancing the science and relevance of remote patient monitoring to gain new scientific insights. He is also a strong advocate for patient involvement and citizen science based approaches to discover improved treatments and cures for unmet medical needs. Eric joined MSD in 2013 from Pfizer where he led a number of initiatives in computational ADME/Tox searching for relationships between pharmaceutical agents, biological targets and physiological responses. Today his primary focus is on the digital transformation of drug discovery and development.
Til Wykes is Professor of Clinical Psychology and Rehabilitation and Vice Dean Psychology and Systems Sciences at the Institute of Psychiatry, Psychology & Neuroscience, King’s College London. She has been involved in research on rehabilitation for many years both in the development of services and the evaluation of innovative psychological treatments for psychosis. She founded and is now Co-Director of the Service User Research Enterprise (SURE), which employs expert researchers with experience of using mental health services.
She edits the Journal of Mental Health and is NIHR Senior Spokesperson on Mental Health Research. She was awarded a Damehood recently for her work in mental health.
Sara is a post-doctoral research associate in the psychology department at King’s College London. She facilitates patient involvement in the RADAR-CNS project. This includes the co-ordination of our patient advisory board. Her role also involves developing a better understanding of processes that improve engagement with mobile technologies in healthcare, using a combination of qualitative and quantitative methods.
Sara is a qualified clinical psychologist and has a PhD in neuropsychology. In her previous work she has researched the feasibility, acceptability and effectiveness of e-health interventions for treatment of mental health problems, including symptoms experienced by people with chronic physical health problems (such as acquired brain injury/stroke). She also has experience of evaluating the psychometric properties of measurement tools in psychology.
Sara has an interest in bringing her knowledge of clinical psychology and behavioural science to the field of e-health with the aim of better understanding the implementation of novel interventions and assessment resources, including remote measurement technology. An important part of this is applying a person-centred approach that focuses on the elements of care, support and treatment that matter most to the patient, their family and carers.
Work Package 9 | Clinical Pathways
Chris Hollis is Professor of Child & Adolescent Psychiatry at the University of Nottingham and Director of the NIHR MindTech Healthcare Technology Co-operative. He trained in psychiatry at the Maudsley Hospital and Institute of Psychiatry, where he was awarded an MRC Training Fellowship and completed his PhD on the long-term adult outcome adolescent-onset psychosis. As Director of MindTech, Chris is passionate about harnessing digital technology and building its evidence-base in mental healthcare by bringing together patients, clinicians, academics and technology developers. He was lead author of ‘Technological Innovations in Mental Healthcare’ in the 2013 Annual Report of England’s Chief medical Officer. Chris chaired the NICE Guideline for schizophrenia and psychosis in children and young people (2011-13) and is currently a member of the NICE ADHD (Update) Guideline Committee. He is a member of Innovate UK’s Digital Health Strategy Group.
Alex is a Human Factors Research Fellow working in the NIHR MindTech MedTech Cooperative within the Division of Psychiatry and Applied Psychology, School of Medicine at the University of Nottingham. Since obtaining her PhD in ‘Medical Device Design for Adolescents’ in 2011 she has researched the design, implementation and evaluation of medical technologies and healthcare systems. She has applied Human Factors methods and Socio-technical systems approaches to a range of medical applications spanning mental and physical health in hospital and community care settings.
In addition to her role on RADAR-CNS investigating the impact of RMT on clinical pathways, Alex’s research interests include patient journey mapping and user experience of mental health services, researching novel technologies for early identification of inpatient deterioration, health promotion in teenagers and elderly populations and medical device development for respiratory conditions, neonatal care and pharmaceutical administration and dosing.
Alex is also leading a strategic collaboration with the Universidad de Guadalajara into healthcare staff wellbeing and patient safety in the Mexican healthcare service. She has worked with a wide range of staff and patient groups and is heavily involved in PPI practices within the NIHR MindTech MIC. Alex leads the Chartered Institute of Ergonomics and Human Factors (CIEHF) Healthcare Steering Committee and provides human factors education and training through multiple institutes and organisations. She is the Human Factors Expert Consultant for the Centre for Healthcare Equipment & Technology Adoption (CHEATA) at Nottingham University Hospitals NHS Trust.
Michael is Senior Research Fellow in the NIHR MindTech MedTech Co-operative, based in the Institute of Mental Health at the University of Nottingham, UK.
He has spent 30 years in research and teaching in the areas of healthcare technology assessment, electronic engineering and computer science.
Additionally he is a member of Faculty of Engineering Bioengineering research group, holds an honorary contract with Nottingham Healthcare NHS Foundation Trust and is Health Economist in the Centre for Healthcare Equipment and Technology Adoption (CHEATA) based in the Nottingham University Hospitals NHS Trust.
In MindTech Mike contributes expertise in design and evaluation of digital health interventions and assistive technologies in mental health and dementia care. He has previously conducted health technology assessments and reviews for National Health Service organisation and industry and recently contributed to a British Standards Institute specification for quality in the development of mobile health apps (PAS 277). Details of publications and other grants are available via ORCID: https://orcid.org/0000-0001-5682-6360
Work Package 10 | Regulation
André W. Broekmans MD PhD is currently Director Regulatory Science at Lygature, The Netherlands.
He has more than twenty-five years regulatory experience, both with the Dutch regulatory agency (as Head of Clinical Assessment and as Chief Executive Officer resp., Dutch Medicines Evaluation Board) and with major pharmaceutical companies (senior management positions with MSD, Schering Plough, Organon). He was successful in gaining regulatory approval for a great number of medicines (small molecules, vaccines, biotech products). In all companies he was involved medical technology initiatives.
He built up his regulatory policy expertise by participating in EMA activities (as chair of the Management Board), ICH Steering Committee (as EFPIA representative) and international trade associations.
André has practiced as a general internist at the Leiden University Hospital where he also did his PhD in thrombosis research.
Steve is a regulatory professional with more than 25 years of applied strategic and tactical delivery of knowledge and experience in International Medical Technology Regulatory Affairs, Quality Assurance and Project Management working in various medical technologies including drug/device combination delivery systems, borderline drug/devices, software medical devices, digital health including ‘Apps’, In-Vitro Diagnostics/companion diagnostics, medical electrical equipment, cosmetics, consumer health products and food supplements.
